Publications

Reeves MQ. Mapping the transcriptional evolution of human metastatic breast cancer. J Clin Invest 134, e183971 (2024). (PMID: 39225091 / PMCID: PMC11364401)

Reeves MQ & Balmain A. Mutations, Bottlenecks, and Clonal Sweeps: How Environmental Carcinogens and Genomic Changes Shape Clonal Evolution during Tumor Progression. Cold Spring Harb Perspect Med 14, a041388 (2024). (PMID: 38052482)

Tanaka M, Lum L, Hu K, Ledezma-Soto C, Superville D, Ng K, Adams Z, Kersten K, Fong F, Krummel M, Reeves MQ. Tumor cell heterogeneity drives spatial organization of the intratumoral immune response in squamous cell skin carcinoma. Bioxriv. doi: 10.1101/2023.04.25.538140 (2023). (PMID: 37162860 / PMCID: PMC10168251)

Fitch B, Zhou M, Situ J, Surianarayanan S, Reeves MQ, Hermiston ML, Wiemels JL, Kogan SC. Decreased IL-10 accelerates B-cell leukemia/lymphoma in a mouse model of pediatric lymphoid leukemia. Blood Advances 6, 854-865 (2022). (PMID: 34727170 / PMCID: PMC8945291)

Wang H, Song X, Liao H, Wang P, Zhang Y, Che L, Zhang J, Zhou Y, Cigliano A, Ament C, Superville D, Ribback S, Reeves M, Pes GM, Liang B, Wu H, Evert M, Calvisi DF, Zeng Y, Chen X. Overexpression of Mothers Against Decapentaplegic Homolog 7 Activates the Yes-Associated Protein/NOTCH Cascade and Promotes Liver Carcinogenesis in Mice and Humans. Hepatology, 74, 248-263 (2021). (PMID: 33368437 / PMCID: PMC8222417)

Dodagatta-Marri E, Meyer DS, Reeves MQ, Paniagua R, To MD, Binnewies M, Broz ML, Mori H, Wu D, Adoumie M, Del Rosario R, Li O, Buchmann T, Liang B, Malato J, Arce Vargus F, Sheppard D, Hann BC, Mirza A, Quezada SA, Rosenblum MD, Krummel MF, Balmain A, Akhurst RJ. α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas. J. Immunother. Cancer 7, 62 (2019). (PMID: 30832732 / PMCID: PMC6399967)

Reeves MQ*, Kandyba E, Harris S, Del Rosario R, Balmain A. Multicolour lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis. Nat. Cell Bio. 20, 699-709 (2018). (PMID: 29802408 / PMCID: PMC6400587)
*Co-corresponding author

Huang PY, Kandyba E, Jabouille A, Sjolund J, Kumar A, Halliwill K, McCreery (Reeves) MQ, Del Rosario R, Kang HC, Wong CE, Seibler J, Beuger V, Pellegrino M, Sciambi A, Eastburn DJ, Balmain A. Lgr6 is a stem cell marker in mouse skin squamous cell carcinoma. Nat. Gen. 49, 1624-31 (2017). (PMID: 28945253 / PMCID: PMC5662105)

McCreery MQ* and Balmain A. Chemical carcinogenesis models of cancer: Back to the future. Ann. Rev. Cancer Bio. 1, 295-312 (2017).
*Co-corresponding author

McCreery MQ, Halliwill KD, Chin D, et al. Evolution of metastasis revealed by mutational landscapes of chemically induced skin cancers. Nat. Med. 21, 1514–20 (2015). (PMID: 26523969 / PMCID: PMC5094808)

Smith CC, Lasater EA, Lin KC, Wang Q, McCreery MQ et al. Crenolanib is a selective type I pan-FLT3 inhibitor. Proc Natl Acad Sci U S A 111, 5319–24 (2014). (PMID: 24623852 / PMCID: PMC3986131)

Rudolph M, McCreery MQ, et al. High chemoselectivity in phenol synthesis. Beilstein J. Org. Chem. 7, 794-801 (2011). (PMID: 21804874 / PMCID: PMC3135103)